Explore our 🎯 Q1 2026 Psychedelic Pipeline Bullseye Charts.

October 21 – 27, 2024

Free Event: Cultivating Connections II (Nov 1, Hybrid)

Register ↗

UCLA’s Ecological Medicine & Psychedelic Studies Initiative is hosting a one-day hybrid event that aims to bridge mental health, Indigenous perspectives, legal rights, city planning, ethnobotany, conservation, ecology, and psychedelic therapies… gosh! Free to attend.

Pα+ Psychedelic Bulletin #178

Psychedelic Alpha ↗

  • Lykos’ Path to FDA Approval Might Include a Third-Party Review of Phase 3 Data, VA Funding of Phase 3 ‘Definitely a Possibility’
  • Precision Psychiatry Platform Under Pressure as Alto’s ALTO-100 Fails in MDD Trial
  • Antidepressant Withdrawal Doesn’t Diminish Psilocybin Efficacy, Compass Study Suggests
  • Massachusetts Miscellany: MAPS Boosts Funding for Yes on Question 4
  • Czech Republic Establishes Unique Category for Low-Risk Psychoactive Substances, Skirting International Drug Controls
  • Other Stories, including: Imperial Wins UK Government Funding for Psilocybin Study; Seaport Therapeutics Scoops $225M Series B; FDA Issues Complete Response Letter to PharmaTher; and more.

Natural Medicine Advisory Bulletin 14

Psychedelic Alpha ↗

Vicente LLP looks at big-picture questions as the program hurtles towards launch. First up are fees and rule changes, before the firm reviews Natural Medicine-related meetings since our last Bulletin in late August.

Tripping on Nothing

The Atlantic ↗

Shayla Love explores how “new, non-hallucinogenic versions of psychedelics are blurring the boundaries of the drug trip. (* Included here as it just missed the cut-off for last week’s Feed.)

October 14 – 20, 2024

Pα+ Psychedelic Bulletin #177

Psychedelic Alpha ↗

  • 5-HT2C Fever: Bright Minds Surges on Longboard’s Seizure Drug Success, But Is It Still a Psychedelics Company?
  • Kasvu Therapeutics: Psychoplastogens, With a TrkB Twist
  • Other stories from the Cambridge Psychedelic Research Group, Awakn Life Sciences, Janssen, AMCP Nexus 2024, and more.

Why voters should pass Question 4

Boston Globe ↗

Bessel van der Kolk encourages Massachusetts voters to get approve the psychedelics question this November.

Lykos Therapeutics Statement on Recent FDA Meeting

Lykos Press Release ↗

Lykos Therapeutics has provided an update on a recent meeting with the FDA re: its MDMA for PTSD New Drug Application. The very brief 100-word statement reveals that the ‘path forward’ for the program will include an additional Phase 3 trial, but could also entail an independent, third-party review of the two existing Phase 3 studies (MAPP1 and MAPP2).

October 7 – 13, 2024

Pα+ Psychedelic Bulletin #176

Psychedelic Alpha ↗

  • Psychedelic Drug Developers Discuss Trial Design at Investor Event
  • Too Close to Call: Massachusetts Voters, Donors, to Decide Fate of State-Level Psychedelic Policy Reforms
  • Mushroom Mirage: SEC Charges Early Psychedelics Stock and Associates Over “Multimillion Dollar Pump-and-Dump” Scheme
  • Other stories.

THE FIGHT FOR QUESTION 4 IN MASSACHUSETTS

As the U.S. elections draw closer coverage of Massachusetts’ Question 4 is heating up, too. If voters endorse the ballot question the state would be tasked with decriminalising certain naturally-occurring psychedelics and establishing a regulated program similar to Oregon’s. But polling shows that the vote is currently too close to call, with donors pouring last-minute funding into the Yes campaign (See Bulletin 176 for more).

Event: ‘Psychedelics in Context’ (Nov 12-13)

More info & Register ↗

This free, hybrid (in-person and virtual) conference will feature multidisciplinary discussions from the likes of Eduardo Schenberg, Katherine Hendy, Claudia Schwartz and Franklin King.

September 30 – October 6, 2024

Pα+ Psychedelic Bulletin #175

Psychedelic Alpha ↗

  • atai Sells a Third of Compass Stake to Raise Cash for In-House Programs
  • Lykos’ Unproven Psychotherapy Hampered Studies, Claim Authors of New Viewpoint
  • Picking Placebos for Psychedelic Studies
  • Small Study of Psilocybin in Severe TRD Among Veterans Shows Promise, But Authors Encourage Tempering Expectations

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