Insights

Read our independent data-driven reporting, analysis and commentary on the psychedelics space: from business and drug development through to policy reform and culture.

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The latest

Dispatch from Breaking Convention 2025: Key Takeaways from Europe’s Largest Psychedelic Summit (Part 2)

From 17–19 April, the UK’s seventh biennial psychedelic conference tackled some of the field’s most urgent questions. In this second instalment, we explore the ethical dilemmas of giving psychedelics to young people, the critical role of therapist selection, how female biology affects drug interactions, the pros and cons of non-hallucinogenic psychoplastogens, and what it really means to integrate psychedelic insights.

Pα+ Psychedelic Bulletin #196: Otsuka Eyes Psychedelic Future in Japan; First Look at Gilgamesh’s Phase 2a Data; ASCP 2025 Preview; VA Sec. Pressed on Psychedelics Plans

Otsuka Eyes Psychedelic Future in Japan with New Infrastructure Drive • ASCP 2025 Preview: Psychedelic Therapies Dominate Clinical Psychopharmacology Agenda • First Look at Gilgamesh’s Phase 2a Data: Psychedelic Candidate Yields Effect Size of ~1.0, But Sparse Details • VA Secretary Pressed for Details on Psychedelics Plans • and more…

Pα+ Psychedelic Bulletin #195: Psychedelics Namechecked in Trump Cabinet Meeting; Noma Therapy Aims to Disrupt At-Home Ketamine; Christian Angermayer on the Politics and Business of Psychedelics, Bitcoin

Psychedelics Namechecked in Trump Cabinet Meeting • Noma Therapy Raises $4.25M, Aims to Disrupt At-Home Ketamine With Insurance-Friendly Approach • Christian Angermayer: Keep Politics Out of Psychedelics—And Bitcoin on the Balance Sheet Christian Angermayer: Keep Politics Out of Psychedelics—And Bitcoin on the Balance Sheet • and more…

March & April 2025 Psychedelic Patent Update: Lykos’ Patent Woes Continue; Filings Provide First Look at Seaport’s 2-Bromo-LSD Program; Delix’s Ergoline Analogues; CaaMTech’s Spinout

Explore or interactive database of psychedelic patent activity in March and April 2025 via our new interface. We also cover a handful of related headlines: from Lykos Therapeutics’ latest MDMA-related patent woes to a patent application-assisted peek under the hood of Seaport Therapeutics’ 2-Bromo-LSD program.

The Library

Through our years of reporting we have covered many of the topics we believe to be important to the present and future of the psychedelics space, broadly defined. However, much of this commentary is scattered across Bulletins, deep dives, special reports and year-end reviews.

The Library provides digestible explainers on salient topics across psychedelic drug development, policy and business: from basic explainers such as “what is psychedelic-assisted therapy?” through to more complex matters such as REMS programs and bifurcated scheduling.

It’s exclusively available to our Pα+ subscribers, with new content added regularly.

Pα+ Library: Bifurcated Scheduling

Pα+ Library: we introduce some of the key concepts in the matter of bifurcated scheduling; a process by which an approved drug product may be placed in a different schedule to the substance itself. As we discuss in this piece, this could have significant repercussions for psychedelic research, legality, and even taxes.

Pα+ Library: Psychedelic REMS

Pα+ Library: we sketch out what a psychedelic REMS might look like, highlighting how these programs could have an outsized impact on the post-approval delivery and accessibility of these treatments.

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