Read our independent data-driven reporting, analysis and commentary on the psychedelics space: from business and drug development through to policy reform and culture.
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Q1 2025 saw roughly $350M flow into the psychedelics industry, the majority of which accrued to a trio of publicly-trader drug developers. Explore key trends, private vs. public dynamics, and what Compass Pathways’ upcoming Phase 3 results could mean for the remainder of 2025.
Dr. Charles Raison has spent decades exploring how ancient practices like meditation, sauna, and psychedelics might interface with modern psychiatry. With roles spanning academia, clinical research, and biotech, he brings a rare perspective to the promises—and pitfalls—of emerging mental health treatments. Here, Psychedelic Alpha’s Josh Hardman sits down with Raison for a wide-ranging interview.
State-regulated psychedelics are on the horizon in Colorado, as The Center Origin in Denver prepares to offer its first psilocybin session. Psychedelic Alpha spoke with Co-Founder and CEO Elizabeth Cooke about how the company became the first licensed psychedelic medicine centre in the Mile High City.
Dr. Shereef Elnahal, former VA Under Secretary for health, discusses how he came to champion psychedelic research within the VA, the promising data in conditions like PTSD and substance use disorders, and the institutional groundwork needed to support the potential roll-out of these therapies at scale. He also shares his opinions on the balancing act between medicalisation and advocacy, and what a coordinated federal approach to psychedelics might, or should, look like.
‘Everything’s On the Table’: VA Secretary Signals Openness to Psychedelics, But Concrete Plans Lacking • Drug Developers Caught Between Tariff Talk, Agency Shake-Ups, and Market Mayhem • Multi-Lab Preprint Study Challenges Replicability of Psilocybin’s Persistent Effects in Mice • Kwan Lab Links 5-HT2A Receptors and Pyramidal Tract to Psilocybin’s Lasting Effects in Mice • FDA Clears Nation’s First Whole-Mushroom Psilocybin Study • Terran vs. Compass Lawsuit Moves Forward as Court Rejects Dismissal • and more…
As New Mexico’s Medical Psilocybin Act Passes, Questions of Access, Provider Risk, and Industry Influence Loom • Arizona’s Oregon-Style Psilocybin Services Bill Gutted and Replaced by Compass Pathways’ Crystalline Polymorph Psilocybin Rescheduling Trigger Law • A Mixed Bag for Compass’ Other Trigger Law Bills • Idaho HJR 4 Passes, Preventing Voters from Legalising Psychoactive Drugs via Ballot Initiatives • Arizona Bill Carving Out $5M for Ibogaine Research Passes House, Working Way through Senate
Through our years of reporting we have covered many of the topics we believe to be important to the present and future of the psychedelics space, broadly defined. However, much of this commentary is scattered across Bulletins, deep dives, special reports and year-end reviews.
The Library provides digestible explainers on salient topics across psychedelic drug development, policy and business: from basic explainers such as “what is psychedelic-assisted therapy?” through to more complex matters such as REMS programs and bifurcated scheduling.
It’s exclusively available to our Pα+ subscribers, with new content added regularly.
Pα+ Library: we introduce some of the key concepts in the matter of bifurcated scheduling; a process by which an approved drug product may be placed in a different schedule to the substance itself. As we discuss in this piece, this could have significant repercussions for psychedelic research, legality, and even taxes.
Pα+ Library: we sketch out what a psychedelic REMS might look like, highlighting how these programs could have an outsized impact on the post-approval delivery and accessibility of these treatments.
Archived versions of our Psychedelic News Feed.
This is an archived version of our Psychedelic News Feed, from September 2 to December 29, 2024.
This is an archived version of our Psychedelic News Feed, from March 4, 2024 – September 1, 2024.
A special version of our Psychedelic News Feed to mark April 1st, 2024.
This is an archived version of our Psychedelic News Feed, from February 5 2024 – March 3 2024.
This is an archived version of our Psychedelic News Feed, from January 8 2024 – February 4 2024.
This is an archived version of our Psychedelic News Feed, from December 11 2023 – January 7 2024.
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